AVNOT-P

Description

• Active Ingredients:
  • Nortriptyline 10 mg: A tricyclic antidepressant (TCA) that helps in relieving neuropathic pain and managing anxiety.
  • Pregabalin 75 mg: An anticonvulsant and anxiolytic that alleviates neuropathic pain and controls seizures.
• Indications:
  • Neuropathic pain
  • Anxiety disorders
  • Fibromyalgia
  • Chronic pain conditions
  • Postherpetic neuralgia
  • Diabetic neuropathy
• Mechanism of Action:
  • Nortriptyline: Inhibits the reuptake of norepinephrine and serotonin, increasing their levels in the brain and helping to relieve pain and improve mood.
  • Pregabalin: Binds to alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system, reducing the release of neurotransmitters involved in pain signaling.
• Benefits:
  • Provides effective relief from neuropathic pain and anxiety.
  • Combines the analgesic effects of nortriptyline with the anticonvulsant properties of pregabalin.
  • Suitable for a variety of chronic pain and anxiety conditions.
• Precautions: Not recommended for individuals with a known hypersensitivity to nortriptyline, pregabalin, or any other components of the formulation. Use with caution in patients with a history of heart disease, renal or hepatic impairment, and those prone to substance abuse. Avoid using during pregnancy or breastfeeding without consulting a healthcare provider.