AVGRAIN-P

Description

• Active Ingredients:
  • Flunarizine Dihydrochloride: A calcium channel blocker that helps prevent migraines by reducing the frequency and severity of migraine attacks.
  • Propranolol Hydrochloride (SR): A beta-blocker that helps prevent migraines by reducing the frequency and intensity of migraine headaches.
• Indications:
  • Prevention of migraines
  • Management of migraine-related symptoms (e.g., headache, nausea, sensitivity to light and sound)
  • Treatment of chronic migraine
• Mechanism of Action:
  • Flunarizine: Works by inhibiting the influx of calcium ions into vascular smooth muscle and the brain, which helps prevent vasospasm and reduces migraine frequency.
  • Propranolol (SR): Blocks beta-adrenergic receptors, reducing the effects of adrenaline and other stress hormones, leading to a decrease in the frequency and intensity of migraine attacks.
• Benefits:
  • Provides effective prevention of migraine attacks.
  • Reduces the frequency and severity of migraines.
  • Combines the benefits of a calcium channel blocker and a beta-blocker for comprehensive migraine management.
  • Improves quality of life for individuals suffering from chronic migraines.
• Precautions: Not recommended for individuals with a known hypersensitivity to flunarizine, propranolol, or any other components of the formulation. Use with caution in patients with a history of depression, asthma, bradycardia, heart failure, or hypotension. Consult a healthcare provider before using during pregnancy or breastfeeding. Regular monitoring may be required for patients with existing cardiovascular conditions.